Review
doi: 10.1007/978-1-4939-6728-5_1.
Methods to Analyze EVs
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- PMID: 27943203
- DOI: 10.1007/978-1-4939-6728-5_1
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Review
Methods to Analyze EVs
Methods Mol Biol.
2017.
Abstract
Research in the field of extracellular vesicles (EVs) is challenged by the small size of the nano-sized particles. Apart from the use of transmission and scanning electron microscopy, established technical platforms to visualize, quantify, and characterize nano-sized EVs were lacking. Recently, methodologies to characterize nano-sized EVs have been developed. This chapter aims to summarize physical principles of novel and conventional technologies to be used in the EV field and to discuss advantages and limitations.
Keywords: Dynamic light scattering; Electron microscopy; Extracellular vesicles; Flow cytometry; Nanoparticle tracking analysis; Resistive pulse sensing.
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