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Review
. 2016 Oct;25(5):311-317.
doi: 10.1053/j.sempedsurg.2016.09.001. Epub 2016 Sep 3.

Surgical treatment of pulmonary metastases in pediatric solid tumors

Todd E Heaton  1 , Andrew M Davidoff  2
Affiliations
Review

Surgical treatment of pulmonary metastases in pediatric solid tumors

Todd E Heaton et al. Semin Pediatr Surg. 2016 Oct.

Abstract

Most children who succumb to solid malignancies do so because of the burden of metastatic disease or due to complications associated with the therapy administered to treat metastatic disease. Approximately one-quarter of children with solid tumors will present with metastatic disease, and an additional 20% ultimately develop metastatic disease, most commonly in the lung. The role of surgery in the treatment of metastatic solid tumors, given its disseminated nature, is not intuitive, yet there are circumstances in which surgical resection of metastatic disease can potentially be curative. However, the utility of surgery is very much dependent on histology, and generally is most appropriate for those malignancies with histologies that are refractory to other adjuvant therapies.

Keywords: Management of metastatic pediatric embryonal tumors; Management of metastatic sarcoma; Pediatric lung metastases; Pediatric solid tumor; Surgical resection of metastatic disease.

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