A Review Of Clinical Trials On LARIAT Device
- PMID: 27957212
- PMCID: PMC4955896
- DOI: 10.4022/jafib.1317
A Review Of Clinical Trials On LARIAT Device
Abstract
The risk of embolic stroke is 5 times higher among patients with atrial fibrillation (AF) compared with those without AF. More than 90% of thrombi form in the left atrial appendage (LAA) in AF. The purpose of this review is to determine the efficacy and safety of the left atrial appendage (LAA) closure via a percutaneous LAA ligation approach, thus preventing a stroke among patients with AF and contraindication to oral anticoagulant therapy.
References
-
- Malladi Vivek, Naeini Payam S, Razavi Mehdi, Collard Charles D, Anton James M, Tolpin Daniel A. Endovascular ablation of atrial fibrillation. Anesthesiology. 2014 Jun;120 (6):1513–9. - PubMed
-
- Go Alan S, Mozaffarian Dariush, Roger Véronique L, Benjamin Emelia J, Berry Jarett D, Borden William B, Bravata Dawn M, Dai Shifan, Ford Earl S, Fox Caroline S, Franco Sheila, Fullerton Heather J, Gillespie Cathleen, Hailpern Susan M, Heit John A, Howard Virginia J, Huffman Mark D, Kissela Brett M, Kittner Steven J, Lackland Daniel T, Lichtman Judith H, Lisabeth Lynda D, Magid David, Marcus Gregory M, Marelli Ariane, Matchar David B, McGuire Darren K, Mohler Emile R, Moy Claudia S, Mussolino Michael E, Nichol Graham, Paynter Nina P, Schreiner Pamela J, Sorlie Paul D, Stein Joel, Turan Tanya N, Virani Salim S, Wong Nathan D, Woo Daniel, Turner Melanie B. Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation. 2013 Jan 1;127 (1):e6–e245. - PMC - PubMed
-
- Wolf P A, Abbott R D, Kannel W B. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991 Aug;22 (8):983–8. - PubMed
-
- Feinberg W M, Blackshear J L, Laupacis A, Kronmal R, Hart R G. Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications. Arch. Intern. Med. 1995 Mar 13;155 (5):469–73. - PubMed
-
- Albers G W, Dalen J E, Laupacis A, Manning W J, Petersen P, Singer D E. Antithrombotic therapy in atrial fibrillation. Chest. 2001 Jan;119 (1 Suppl):194S–206S. - PubMed
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