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Review
. 2015 Dec 31;8(4):1288.
doi: 10.4022/jafib.1288. eCollection 2015 Dec.

Atrial Fibrillation in Cardiac Sarcoidosis

Affiliations
Review

Atrial Fibrillation in Cardiac Sarcoidosis

Davendra Mehta et al. J Atr Fibrillation. .

Abstract

Sarcoidosis is a systemic granulomatous disease that affects the myocardium. Although ventricular arrhythmias are well known manifestations of cardiac involvement, there is increasing evidence that a significant proportion of patients with cardiac sarcoidosis (CS) also have atrial arrhythmias, atrial fibrillation being the most frequent. The incidence and mechanism of atrial fibrillation in CS is not precisely known. The management of atrial fibrillation in patients with CS is currently done according to the general guidelines for management of atrial fibrillation. Evidence is emerging regarding the additional role of immunosuppression for the treatment of atrial arrhythmias in CS. This paper reviews the incidence, possible mechanisms and treatment strategies of atrial fibrillation in patients with CS.

Keywords: Arrhythmia Control; Atrial Fibrillation; Cardiac Sarcoidosis; Outcomes; Sarcoidosis.

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Figures

Figure 1.
Figure 1.. Postero-anterior and anterior-posterior views of electro-anatomical voltage map of the left atrium (CARTO) in a 45 year old patient with paroxysmal atrial fibrillation prior to ablation. Left atrial appendage is not included. There is extensive atrial scar represented by areas of low voltage. Purple areas had voltage above 0.5 V rest of the left atrium had voltage <0.5V, red areas <0.05 V and thus represent atrial scar

References

    1. Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am. J. Respir. Crit. Care Med. 1999 Aug;160 (2):736–55. - PubMed
    1. Vignaux Olivier, Dhote Robin, Duboc Denis, Blanche Philippe, Devaux Jean-Yves, Weber Simon, Legmann P. Detection of myocardial involvement in patients with sarcoidosis applying T2-weighted, contrast-enhanced, and cine magnetic resonance imaging: initial results of a prospective study. J Comput Assist Tomogr. 2002 Nov 20;26 (5):762–7. - PubMed
    1. Smedema Jan-Peter, Snoep Gabriel, van Kroonenburgh Marinus P G, van Geuns Robert-Jan, Dassen Willem R M, Gorgels Anton P, Crijns Harry J G M. Cardiac involvement in patients with pulmonary sarcoidosis assessed at two university medical centers in the Netherlands. Chest. 2005 Jul;128 (1):30–5. - PubMed
    1. Birnie David H, Sauer William H, Bogun Frank, Cooper Joshua M, Culver Daniel A, Duvernoy Claire S, Judson Marc A, Kron Jordana, Mehta Davendra, Cosedis Nielsen Jens, Patel Amit R, Ohe Tohru, Raatikainen Pekka, Soejima Kyoko. HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis. Heart Rhythm. 2014 Jul;11 (7):1305–23. - PubMed
    1. Cain Matthew A, Metzl Mark D, Patel Amit R, Addetia Karima, Spencer Kirk T, Sweiss Nadera J, Beshai John F. Cardiac sarcoidosis detected by late gadolinium enhancement and prevalence of atrial arrhythmias. Am. J. Cardiol. 2014 May 1;113 (9):1556–60. - PubMed

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