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. 2016 Feb 21;17(1):61-66.
doi: 10.17305/bjbms.2016.1482.

Radiopacity of alloplastic bone grafts measured with cone beam computed tomography: An analysis in rabbit calvaria

Cristina Bucchi  1 , Eduardo Borie, Alain Arias, Fernando José Dias, Ramón Fuentes
Affiliations

Radiopacity of alloplastic bone grafts measured with cone beam computed tomography: An analysis in rabbit calvaria

Cristina Bucchi et al. Bosn J Basic Med Sci. .

Abstract

Availability of adequate bone structure for dental implants is still a problem in dentistry. Alloplastic grafts, which promote bone regeneration, are used as bone substitutes in orthopedic and oral surgical procedures. The aim of this study was to evaluate the radiopacity of three different synthetic bone grafts in rabbit calvaria, over 3 months, using cone beam computed tomography (CBCT). Four critical-size defects were made on the calvaria of 11 rabbits. The lesions were classified into three groups according to the alloplastic grafts they received: Osteon® 70/30, Osteon collagen®, and Osteon II® groups. The fourth group received blood clot, and served as a control. The bone samples were collected and analyzed with CBCT after the 1st, 2nd, and 3rd month. One month after surgery, the lesions that received Osteon® 70/30 and Osteon collagen® grafts showed the highest radiopacity compared to the lesions with Osteon II® and blood clot. After the 2nd month, the radiopacity values between the three groups that received the grafts were more similar compared to the group with blood clot. After the 3rd month, the lesions with Osteon® 70/30 graft showed the highest radiopacity values, followed by Osteon collagen® and Osteon II® groups. The group that received blood clot showed the lowest radiopacity values. In conclusion, the grafts used in this study had higher radiopacity values compared to blood clot. Among the grafts used, the Osteon® 70/30 graft showed the highest radiopacity values in the 3-month period.

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Figures

FIGURE 1
FIGURE 1
Radiopacity values of three bone grafts and blood clot. (A) Radiopacity data grouped by each month. (B) Radiopacity values over the 3-month period.
FIGURE 2
FIGURE 2
Cone beam computed tomography image showing the radiopacity (black arrows) of the three biomaterials and blood clot. (A-D) After the 1st month and (E-H) after 3 months of application.
FIGURE 3
FIGURE 3
Statistical analysis of radiopacity values for each month. (A) 1st month; (B) 2nd month; and (C) 3rd month. a, b, and c – statistically significant difference (p < 0.05).
See this image and copyright information in PMC

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