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. 1989 Aug;9(8):3543-7.
doi: 10.1128/mcb.9.8.3543-3547.1989.

Characterization and expression of a spliced leader RNA in the parasitic nematode Ascaris lumbricoides var. suum

T W Nilsen  1 , J Shambaugh, J Denker, G Chubb, C Faser, L Putnam, K Bennett
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Characterization and expression of a spliced leader RNA in the parasitic nematode Ascaris lumbricoides var. suum

T W Nilsen et al. Mol Cell Biol. 1989 Aug.

Abstract

The parasitic nematode Ascaris spp. contains a 22-nucleotide spliced-leader (SL) sequence identical to the trans-SL previously described in Caenorhabditis elegans and other nematodes. The SL comprises the first 22 nucleotides of a approximately 110-base RNA and is transcribed by RNA polymerase II. The SL RNA contains a trimethylguanosine cap and a consensus Sm binding site. Furthermore, the Ascaris SL RNA has the potential to adopt a secondary structure which is nearly identical to potential secondary structures of similar SL RNAs in C. elegans and Brugia malayi.

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References

    1. Proc Natl Acad Sci U S A. 1975 Aug;72(8):2959-63 - PubMed
    1. Trends Genet. 1988 Nov;4(11):305-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1979 Apr;76(4):1760-4 - PubMed
    1. Methods Enzymol. 1980;65(1):65-74 - PubMed
    1. Nucleic Acids Res. 1981 Jan 10;9(1):133-48 - PubMed

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