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Comment
. 2016 Dec 13;24(6):779-781.
doi: 10.1016/j.cmet.2016.11.013.

Assisted Living in the Atheroma: Elderly Macrophages Promote Plaques

Peter Libby  1
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Assisted Living in the Atheroma: Elderly Macrophages Promote Plaques

Peter Libby. Cell Metab. .
Free article

Abstract

Age dominates as a risk factor for human atherosclerosis, yet the underlying mechanisms remain elusive. A recent report described accumulation of senescent cells in atheromata of hypercholesterolemic mice and provides novel insights into how genes expressed by aging cells associate with the characteristics of human plaques implicated in cardiovascular events.

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