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Comment
. 2017 Mar;55(3):681-685.
doi: 10.1128/JCM.02283-16. Epub 2016 Dec 14.

The Ongoing Genetic Adaptation of Streptococcus pneumoniae

Sandra S Richter  1 , Daniel M Musher  2
Affiliations
Comment

The Ongoing Genetic Adaptation of Streptococcus pneumoniae

Sandra S Richter et al. J Clin Microbiol. 2017 Mar.

Abstract

Streptococcus pneumoniae has demonstrated a remarkable ability to adapt during the conjugate vaccine era. The increasing incidence of serotype 35B disease and emergence of a multidrug-resistant clone reported in this issue of the Journal of Clinical Microbiology (L. Olarte et al., J Clin Microbiol 55:724-734, 2017, https://doi.org/10.1128/JCM.01778-16) underscore the limitations of pneumococcal vaccines that target the polysaccharide capsule.

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Figures

FIG 1
FIG 1
Changing proportions of serotypes of penicillin-nonsusceptible (MIC of ≥0.12 μg/ml) Streptococcus pneumoniae (PNSP) isolates in the United States during the pneumococcal conjugate vaccine (PCV) era (14, 15).
See this image and copyright information in PMC

Comment on

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