Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Nov 23;4(11):e1148.
doi: 10.1097/GOX.0000000000001148. eCollection 2016 Nov.

New B-cell Lymphomas in the Setting of a Previous Rare Breast Implant-Associated B-cell Lymphoma

Alison Messer  1 , Helena Jenkinson  1 , Wei Wang  1 , Madeleine Duvic  1
Affiliations
Case Reports

New B-cell Lymphomas in the Setting of a Previous Rare Breast Implant-Associated B-cell Lymphoma

Alison Messer et al. Plast Reconstr Surg Glob Open. .

Abstract

We present a follow-up of a patient who underwent right-sided subtotal mastectomy and placement of right-sided saline implant in 1968 for a phyllodes tumor and then in 2012 was diagnosed with a rare B-cell type lymphoma of the right breast. In 2015, she was diagnosed with diffuse large B-cell lymphoma involvement of the left breast and left leg and experienced subsequent self-regression of leg lesions without therapy.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
A, Left breast core needle biopsy showing lymphoma cells with large nuclei and one-to-several prominent nucleoli admixed (hematoxylin and eosin [H&E]). B, Immunohistochemistry (IHC) showing positivity of tumor cells to CD20 in a perivascular distribution similar to the H&E stain (IHC CD20). C, A subset of the tumor cells stain positive for B-cell lymphoma 6 (IHC BCL-6).
See this image and copyright information in PMC

References

    1. Cheah CY, Campbell BA, Seymour JF. Primary breast lymphoma. Cancer Treat Rev. 2014;40:900–908. - PubMed
    1. Smith BK, Gray SS. Large B-cell lymphoma occurring in a breast implant capsule. Plast Reconstr Surg. 2014;134:670e–671e. - PubMed
    1. Duvic M, Moore D, Menter A, et al. Cutaneous T-cell lymphoma in association with silicone breast implants. J Am Acad Dermatol. 1995;32:939–942. - PubMed
    1. Sendagorta E, Ledo A. Sézary syndrome in association with silicone breast implant. J Am Acad Dermatol. 1995;33:1060–1061. - PubMed
    1. Chastain EC, Duncavage EJ. Clinical prognostic biomarkers in chronic lymphocytic leukemia and diffuse large B-cell lymphoma. Arch Pathol Lab Med. 2015;139:602–607. - PubMed

Publication types

LinkOut - more resources