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Review
. 2017 Jan;77(1).
doi: 10.1111/aji.12612. Epub 2016 Dec 15.

Effects of TSLP on obstetrical and gynecological diseases

Yuan Zhang  1 , Li-Ping Jin  1   2
Affiliations
Review

Effects of TSLP on obstetrical and gynecological diseases

Yuan Zhang et al. Am J Reprod Immunol. 2017 Jan.

Abstract

Thymic stromal lymphopoietin (TSLP) is produced mainly by epithelial cells and was originally found to stimulate the growth and activation of B cells, but it is now shown to function on both hematopoietic and non-hematopoietic cell lineages. Despite a number of studies focusing on the role of TSLP in Th2 response for allergic disorders, it is becoming increasingly evident that TSLP may also be involved in multiple other disease states. This review will focus on recent advances on the effects of TSLP on obstetrical and gynecological diseases, including pregnancy failure, endometriosis, and cervical cancer.

Keywords: cervical cancer; endometriosis; pregnancy; thymic stromal lymphopoietin (TSLP).

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