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Review
. 2016 Sep;57(3):E115-E120.

History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines

I Barberis  1 , P Myles  2 , S K Ault  3 , N L Bragazzi  1 , M Martini  4
Affiliations
Review

History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines

I Barberis et al. J Prev Med Hyg. 2016 Sep.

Abstract

Influenza is a highly infectious airborne disease with an important epidemiological and societal burden; annual epidemics and pandemics have occurred since ancient times, causing tens of millions of deaths. A hundred years after this virus was first isolated, influenza vaccines are an important influenza prevention strategy and the preparations used display good safety and tolerability profiles. Innovative tools, such as recombinant technologies and intra-dermal devices, are currently being investigated in order to improve the immunological response. The recurring mutations of influenza strains has prompted the recent introduction of a quadrivalent inactivated vaccine. In the near future, scientific research will strive to produce a long-lasting universal vaccine containing an antigen that will offer protection against all influenza virus strains.

Keywords: History of medicine; Influenza; Vaccination.

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References

    1. Gasparini R, Amicizia D, Lai PL, Bragazzi NL, Panatto D. Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part I: Influenza life-cycle and currently available drugs. J Prev Med Hyg. 2014;55:69–85. - PMC - PubMed
    1. Gasparini R, Amicizia D, Lai PL, Bragazzi NL, Panatto D. Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virus. J Prev Med Hyg. 2014;55:109–129. - PMC - PubMed
    1. Hause BM, Collin EA, Liu R, Huanq B, Shenq Z, Lu W, Wanq D, Nelson EA, Li F. Characterization of a novel influenza virus in cattle and Swine: proposal for a new genus in the Orthomyxoviridae family. MBio. 2014;5:e00031–e00114. - PMC - PubMed
    1. Collin EA, Sheng Z, Lang Y, Ma W, Hause BM, Li F. Cocirculation of two distinct genetic and antigenic lineages of proposed influenza D virus in cattle. J Virol. 2015;89:1036–1042. - PMC - PubMed
    1. Ducatez MF, Pelletier C, Meyer G. Influenza D virus in cattle, France, 2011-2014. Emerg Infect Dis. 2015;21:368–371. - PMC - PubMed

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