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Case Reports
. 2017 Jan;23(1):146-147.
doi: 10.3201/eid2301.160923.

Hepatitis E Virus Infection after Platelet Transfusion in an Immunocompetent Trauma Patient

Emmanuelle Loyrion, Thibaut Trouve-Buisson, Patricia Pouzol, Sylvie Larrat, Thomas Decaens, Jean-Francois Payen
Case Reports

Hepatitis E Virus Infection after Platelet Transfusion in an Immunocompetent Trauma Patient

Emmanuelle Loyrion et al. Emerg Infect Dis. 2017 Jan.

Abstract

Hepatitis E virus (HEV) infection causes acute liver disease, but severe infections are rare in immunocompetent patients. We describe a case of HEV infection in a previously healthy male trauma patient in France who received massive transfusions. Genotyping confirmed HEV in a transfused platelet pool and the donor.

Keywords: HEV; blood transfusion; cholestasis; contaminated blood products; hepatitis E virus; immunocompetent; injury; jaundice; opportunistic infection; platelet transfusion; transfusion; trauma; viruses.

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Figures

Figure
Figure
Time course of liver blood test results from a trauma patient in France who was transfused with an HEV-contaminated blood platelet pool on day 5 posttrauma. ALT, alanine aminotransferase; AP, alkaline phosphatase; AST, aspartate aminotransferase; GGT, gamma glutamyl transferase; HEV, hepatitis E virus; open-C, open cholecystectomy; per-C, percutaneous cholecystectomy.
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