Easy Stress Relief by EZH2
- PMID: 27984719
- DOI: 10.1016/j.cell.2016.11.051
Easy Stress Relief by EZH2
Abstract
While we are beginning to appreciate the cellular roles played by long noncoding RNAs, the function of transcripts emerging from repetitive genomic regions remains enigmatic. In this issue, Zovoilis et al. report that the polycomb protein EZH2, upon heat shock, facilitates transcription of stress-responsive genes by inducing the degradation of the transcriptional repressor B2 repeat RNA.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment in
-
Destabilization of B2 RNA by EZH2 Activates the Stress Response.Cell. 2016 Dec 15;167(7):1788-1802.e13. doi: 10.1016/j.cell.2016.11.041. Cell. 2016. PMID: 27984727 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources