Stressing Out About RAD52
- PMID: 27984741
- DOI: 10.1016/j.molcel.2016.11.036
Stressing Out About RAD52
Abstract
The role of mammalian RAD52 has been mysterious due to the lack of a strong DNA repair phenotype of RAD52-deficient cells. In this issue of Molecular Cell, studies by Bhowmick et al. (2016) and Sotiriou et al. (2016) reveal an unexpected role for RAD52 in promoting DNA synthesis following replication stress.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress.Mol Cell. 2016 Dec 15;64(6):1117-1126. doi: 10.1016/j.molcel.2016.10.037. Mol Cell. 2016. PMID: 27984745
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Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.Mol Cell. 2016 Dec 15;64(6):1127-1134. doi: 10.1016/j.molcel.2016.10.038. Mol Cell. 2016. PMID: 27984746 Free PMC article.
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