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Review
. 2017 May;15(5):619-630.
doi: 10.1016/j.cgh.2016.10.021. Epub 2016 Oct 28.

Endoscopic Bariatric and Metabolic Therapies: Surgical Analogues and Mechanisms of Action

Pichamol Jirapinyo  1 , Christopher C Thompson  2
Affiliations
Review

Endoscopic Bariatric and Metabolic Therapies: Surgical Analogues and Mechanisms of Action

Pichamol Jirapinyo et al. Clin Gastroenterol Hepatol. 2017 May.

Abstract

Obesity is a worsening pandemic with numerous related comorbid illnesses. Conservative management including lifestyle modification and medications have limited efficacy. In contradistinction, bariatric surgery is effective, however, with substantial cost and non-negligible morbidity and mortality. As such, a small percentage of eligible patients undergo surgery. Over the past decade, endoscopic bariatric and metabolic therapies have been introduced as a less invasive option for the treatment of obesity and its related comorbid illnesses. This article reviews major endoscopic bariatric and metabolic therapies, their surgical analogues, and proposed mechanisms of action. Clinical trial data for each device also are discussed.

Keywords: Aspire; Bariatric; Diabetes; Duo; EBMT; EBT; ESG; EndoBarrier; Endoscopic Sleeve Gastroplasty; Endoscopy; GLP-1; Gastric Balloon; Ghrelin; IMAS; Incretin; Magnetic; Metabolic; Obalon; Obesity; Orbera; POSE; PYY.

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Conflict of interest statement

Pichamol Jirapinyo MD

No Conflict of Interest

Figures

Figure 1
Figure 1
Gastric Interventions and Their Surgical Correlates
Figure 2
Figure 2
Gastric Interventions and Their Surgical Correlates (continued)
Figure 3
Figure 3
Gastric and Small Bowel Interventions Without Clear Surgical Analogues
Figure 4
Figure 4
Small Bowel Interventions and Their Surgical Correlates
See this image and copyright information in PMC

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