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Case Reports
. 2016 Nov-Dec;7(6):520-522.
doi: 10.4103/2229-5178.193923.

Nekam's disease

Chintaginjala Aruna  1 , D V S B Ramamurthy  1 , T Neelima  2 , Haritha Bandaru  1
Affiliations
Case Reports

Nekam's disease

Chintaginjala Aruna et al. Indian Dermatol Online J. 2016 Nov-Dec.

Abstract

Keratosis lichenoides chronica also known as Nekam's disease is a rare mucocutaneous disorder, characterized clinically by asymptomatic violaceous keratotic papules arranged in linear, reticular, or plaque form usually on the trunk and extremities and histologically by interface dermatitis. The disease is considered rare with only 128 cases being reported in the literature till date and very few from India. We report a case of a 40-year-old man who presented with constellation of features of lichen planus, seborrheic dermatitis, and apthous ulcers, which upon workup was found to be Nekam's disease.

Keywords: Interface dermatitis; Keratosis lichenoids chronica; Nekam's disease.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Multiple, violaceous, hyperkeratotic, scaly papules and plaques over extensor aspects of forearms (a), over lateral aspect of ankle (b), scrotum (c). Lesions over forearm arranged in a linear fashion (d)
Figure 2
Figure 2
Seborrheic dermatitis like picture over medial aspect of eyebrows (a), ala nasi (b), erosions with violaceous margin over inner aspect of prepuce (c), apthous ulcers over inner aspect of upper lip (d), erosions over hard palate (e)
Figure 3
Figure 3
Whole mount of the skin bit showing alternate areas of acanthosis and atrophy, hyperkeratosis, inflammatory infiltrates, and follicular plugging (a) (H and E, ×40) (b). Close up view of parakeratosis and (c) follicular plugging (H and E, ×10)
Figure 4
Figure 4
Inflammatory infiltrate obscuring dermoepidermal junction (a) (H and E, ×10). Areas of vacuolar alteration of cells (b) (H and E, ×40). Increased plasma cell infiltrate (c) (H and E, ×100). Dilated dermal capillaries (d) (H and E, ×40)
See this image and copyright information in PMC

References

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