Predictors of HIV Care Engagement, Antiretroviral Medication Adherence, and Viral Suppression Among People Living with HIV Infection in St. Petersburg, Russia
- PMID: 27990579
- PMCID: PMC5476511
- DOI: 10.1007/s10461-016-1638-9
Predictors of HIV Care Engagement, Antiretroviral Medication Adherence, and Viral Suppression Among People Living with HIV Infection in St. Petersburg, Russia
Abstract
Over 1 million HIV infections have been diagnosed in Russia, and HIV care uptake and viral suppression are very low. 241 HIV-positive individuals in St. Petersburg were enrolled through social networks, provided blood for viral load testing, and completed measures of medication-taking adherence, readiness, and self-efficacy; psychosocial well-being; and substance use. Outcomes included attending an HIV care appointment in the past 6 months, >90% ART adherence, and undetectable viral load. 26% of participants had no recent care appointment, 18% had suboptimal adherence, and 56% had detectable viral load. Alcohol use consistently predicted all adverse health outcomes. Having no recent care visit was additionally associated with being single and greater past-month drug injection frequency. Poor adherence was additionally predicted by lower medication-taking self-efficacy and lower anxiety. Detectable viral load was additionally related to younger age. Comprehensive interventions to improve HIV care in Russia must address substance abuse, anxiety, and medication-taking self-efficacy.
Keywords: HIV care linkage and retention; HIV medical care; HIV services; HIV-positive; Persons living with HIV; Russia.
Conflict of interest statement
Compliance with Ethical Standards:
Author Yuri A. Amirkhanian declares that he/she has no conflict of interest.
Author Jeffrey A. Kelly declares that he/she has no conflict of interest.
Author Wayne J. DiFranceisco declares that he/she has no conflict of interest.
Author Anna V. Kuznetsova declares that he/she has no conflict of interest.
Author Sergey S. Tarima declares that he/she has no conflict of interest.
Author Alexey A. Yakovlev declares that he/she has no conflict of interest.
Author Vladimir B. Musatov declares that he/she has no conflict of interest.
Ethical approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent: Informed consent was obtained from all individual participants included in the study.
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