Different efficacy of ramucirumab in patients with metastatic gastric and gastroesophageal junction cancer according to ECOG performance status

G Roviello¹, C Pacifico², K Polom³, F Roviello³, D Generali^{4

5}

Affiliations

¹ Unit of Medical Oncology, Department of Oncology, Ospedale San Donato, Arezzo.
² Department of Medical, Surgical and Neurological Sciences, University Hospital of Siena, Radiotherapy Unit, Siena.
³ Unit of General and Minimally Invasive Surgery, Surgery and Neuroscience; University of Siena, Siena.
⁴ Unit of Molecular Therapy and Pharmacogenomic, ASST Cremona, Cremona.
⁵ Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Comment

G Roviello et al. Ann Oncol. 2017.

. 2017 Mar 1;28(3):665-666.

doi: 10.1093/annonc/mdw657.

G Roviello¹, C Pacifico², K Polom³, F Roviello³, D Generali^{4

5}

¹ Unit of Medical Oncology, Department of Oncology, Ospedale San Donato, Arezzo.
² Department of Medical, Surgical and Neurological Sciences, University Hospital of Siena, Radiotherapy Unit, Siena.
³ Unit of General and Minimally Invasive Surgery, Surgery and Neuroscience; University of Siena, Siena.
⁴ Unit of Molecular Therapy and Pharmacogenomic, ASST Cremona, Cremona.
⁵ Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

No abstract available

Comment in

Consideration of an association between performance status and ramucirumab efficacy.
Yoon HH, Bendell JC, Wainberg ZA. Yoon HH, et al. Ann Oncol. 2017 Apr 1;28(4):902-903. doi: 10.1093/annonc/mdw688. Ann Oncol. 2017. PMID: 28203696 No abstract available.

Ramucirumab combined with FOLFOX as front-line therapy for advanced esophageal, gastroesophageal junction, or gastric adenocarcinoma: a randomized, double-blind, multicenter Phase II trial.
Yoon HH, Bendell JC, Braiteh FS, Firdaus I, Philip PA, Cohn AL, Lewis N, Anderson DM, Arrowsmith E, Schwartz JD, Gao L, Hsu Y, Xu Y, Ferry D, Alberts SR, Wainberg ZA. Yoon HH, et al. Ann Oncol. 2016 Dec;27(12):2196-2203. doi: 10.1093/annonc/mdw423. Epub 2016 Oct 20. Ann Oncol. 2016. PMID: 27765757 Free PMC article. Clinical Trial.