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Review
. 2016 Dec 8:9:1179-1189.
doi: 10.2147/JPR.S115068. eCollection 2016.

Combining pain therapy with lifestyle: the role of personalized nutrition and nutritional supplements according to the SIMPAR Feed Your Destiny approach

Manuela De Gregori  1 , Carolina Muscoli  2 , Michael E Schatman  3 , Tiziana Stallone  4 , Fabio Intelligente  5 , Mariangela Rondanelli  6 , Francesco Franceschi  7 , Laura Isabel Arranz  8 , Silvia Lorente-Cebrián  9 , Maurizio Salamone  10 , Sara Ilari  11 , Inna Belfer  12 , Massimo Allegri  13
Affiliations
Review

Combining pain therapy with lifestyle: the role of personalized nutrition and nutritional supplements according to the SIMPAR Feed Your Destiny approach

Manuela De Gregori et al. J Pain Res. .

Abstract

Recently, attention to the lifestyle of patients has been rapidly increasing in the field of pain therapy, particularly with regard to the role of nutrition in pain development and its management. In this review, we summarize the latest findings on the role of nutrition and nutraceuticals, microbiome, obesity, soy, omega-3 fatty acids, and curcumin supplementation as key elements in modulating the efficacy of analgesic treatments, including opioids. These main topics were addressed during the first edition of the Study In Multidisciplinary Pain Research workshop: "FYD (Feed Your Destiny): Fighting Pain", held on April 7, 2016, in Rome, Italy, which was sponsored by a grant from the Italian Ministry of Instruction on "Nutraceuticals and Innovative Pharmacology". The take-home message of this workshop was the recognition that patients with chronic pain should undergo nutritional assessment and counseling, which should be initiated at the onset of treatment. Some foods and supplements used in personalized treatment will likely improve clinical outcomes of analgesic therapy and result in considerable improvement of patient compliance and quality of life. From our current perspective, the potential benefit of including nutrition in personalizing pain medicine is formidable and highly promising.

Keywords: nutritional supplements; pain; personalized nutrition.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Scheme of summary of FYD workshop. Abbreviation: FYD, Feed Your Destiny.
See this image and copyright information in PMC

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References

    1. Di Tella M, Castelli L, Colonna F, et al. Theory of mind and emotional functioning in fibromyalgia syndrome: an investigation of the relationship between social cognition and executive function. PLoS One. 2015;10(1):e0116542. - PMC - PubMed
    1. Burri A, Ogata S, Livshits G, Williams F. The association between chronic widespread musculoskeletal pain, depression and fatigue is genetically mediated. PLoS One. 2015;10(11):e0140289. - PMC - PubMed
    1. Smith SB, Reenilä I, Männistö PT, et al. Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain. Pain. 2014;155(11):2390–2399. - PMC - PubMed
    1. Leonard BE. Pain, depression and inflammation: are interconnected causative factors involved? Mod Trends Pharmacopsychiatri. 2015;30:22–35. - PubMed
    1. Lorente-Cebrián S, Costa AG, Navas-Carretero S, et al. An update on the role of omega-3 fatty acids on inflammatory and degenerative diseases. J Physiol Biochem. 2015;71(2):341–349. - PubMed