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Case Reports
. 2016 Nov 14:10:692.
doi: 10.3332/ecancer.2016.692. eCollection 2016.

Sinonasal glomangiopericytoma treated with preoperative embolisation and endoscopic sinus surgery

Elizabeth Psoma  1 , Petros D Karkos  2 , Stamatia Dova  2 , Michail Gavriilidis  1 , Konstantinos Markou  2 , Constantinos Kouskouras  1 , Afroditi Haritanti  1 , Stefanos Finitsis  1
Affiliations
Case Reports

Sinonasal glomangiopericytoma treated with preoperative embolisation and endoscopic sinus surgery

Elizabeth Psoma et al. Ecancermedicalscience. .

Abstract

Sinonasal glomangiopericytoma is a benign rare tumour of pericytes that accounts for less than 0.5% of all sinonasal tumours. It is an indolent tumour with a macroscopic appearance of common inflammatory polyps. We report the case of a 55-year-old male who presented with right nasal obstruction. CT and MRI examinations demonstrated a soft-tissue mass that obstructed mainly the right nasal cavity. Biopsy revealed glomangiopericytoma. The tumour was treated with preoperative embolisation followed by complete endoscopic resection. Very few cases have been reported to be treated in this way.

Keywords: embolization; endoscopic sinus surgery; glomangiopericytoma; nose; sinus.

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Figures

Figure 1.
Figure 1.. CT showing a soft tissue mass from the right nasal cavity extending to the posterior ethmoid air cells. Inflammatory changes are present to the right sphenoid sinus.
Figure 2.
Figure 2.. MRI (a) T1WI showing mainly hypointense mass in the right nasal cavity and posterior ethmoid air cells with retained secretions and inflammatory changes to the left ethmoid air cells (b) T1WI GD axial and (c) Coronal images showing the expansive soft tissue mass well-defined with intense enhancement (d) T2WI sagittal plane showing high signal intensity of the lesion.
Figure 3.
Figure 3.. (a) Tumour of the nasal mucosa with moderate cellularity composed of ovoid to spindle cells with ovoid bland nuclei (H+E X 100) (b) Tumour cells are positive for vimentin (Immunostain X 200) (c) Tumour cells are focally positive for SMA (Immunostain X 200) (d) Few tumour cells are positive for CD34 (Immunostain X 200) (e) tumour cells show moderate to strong nuclear positivity for β-Catenin (ImmunostainX200) (f) Tumour cells of the nasal mucosa (H+E).
Figure 4.
Figure 4.. DSA (a, b) angiography showing branches of the right sphenopalatine artery (c, d) angiography after embolisation showed complete devascularisation of the tumour.
Figure 5.
Figure 5.. Intraoperative photograph showing the lesion arising from the middle turbinate.
See this image and copyright information in PMC

References

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