Idiopathic Multifocal Choroiditis

Abstract

Idiopathic multifocal choroiditis (MFC) and/or punctate inner choroidopathy (PIC) describe a chronic progressive bilateral inflammatory chorioretinopathy that predominantly affect healthy myopic white women with no known associated systemic or ocular diseases. The principal sites of involvement are the retinal pigment epithelium (RPE) and outer retinal spaces; the choroid is not affected during the active phase of the disease. Idiopathic MFC with atrophy is a recently described variant. Although there is no generally accepted standard treatment, anti-inflammatory and anti-VEGF (vascular endothelial growth factor) agents are necessary in the acute stage to control the inflammation and choroidal neovascularization (CNV).

Keywords: Idiopathic Multifocal Choroiditis; Panuveitis; Punctate Inner Choroidopathy.

Figure 1

Color fundus photograph of a 21-year-old man, presenting with blurred vision and floaters in both eyes over several months. Note multiple, diffuse and discrete nummular outer retinal/choroidal white spots and equatorial linear/curvilinear streak lesions (Schlaegel lines) in the left eye.