Germ Cells Get by with a Little Cannibalistic Help from Their Friends
- PMID: 27997820
- DOI: 10.1016/j.devcel.2016.12.003
Germ Cells Get by with a Little Cannibalistic Help from Their Friends
Abstract
During development, primordial germ cells (PGCs) navigate a complex journey to generate the germline. In a recent paper in Nature Cell Biology, Nance and colleagues (Abdu et al., 2016) have discovered an unexpected step along the way: PGCs get cut in half by endodermal cells.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Developmentally programmed germ cell remodelling by endodermal cell cannibalism.Nat Cell Biol. 2016 Dec;18(12):1302-1310. doi: 10.1038/ncb3439. Epub 2016 Nov 14. Nat Cell Biol. 2016. PMID: 27842058 Free PMC article.
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