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Comment
. 2017 Jan;66(1):20-22.
doi: 10.2337/dbi16-0049.

Exocrine and Endocrine Interactions in Cystic Fibrosis: A Potential Key to Understanding Insulin Secretion in Health and Disease?

Claudio Cobelli  1 , Adrian Vella  2
Affiliations
Comment

Exocrine and Endocrine Interactions in Cystic Fibrosis: A Potential Key to Understanding Insulin Secretion in Health and Disease?

Claudio Cobelli et al. Diabetes. 2017 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Multiple gastrointestinal factors could influence the insulin secretory response to a meal challenge. These include the rate of gastric emptying and other factors that directly or indirectly affect motility, enteroendocrine secretion, and intraluminal digestion. Tests of β-cell function may challenge different components of the insulin secretory apparatus. However, it is important to remember that the β-cell secretory response (Φ) must be considered in light of the insulin action (Si), as illustrated in the figure, where identical Φ reflects two different states of glucose tolerance. IGT, impaired glucose tolerance; NGT, normal glucose tolerance.
See this image and copyright information in PMC

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