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Comment
. 2017 Jan 3;114(1):15-16.
doi: 10.1073/pnas.1618747114. Epub 2016 Dec 20.

Sensing danger

Luciano A Marraffini  1
Affiliations
Comment

Sensing danger

Luciano A Marraffini. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Regulation of CRISPR-Cas activity by QS. At low cell density, low autoinducer (pink dot) concentrations result in the repression of CRISPR-cas loci through the QS pathway, keeping the CRISPR-Cas immune response at a minimum. In contrast, at high densities of bacteria (when they are most susceptible to phage attack) the increase in the concentration of autoinducer triggers the de-repression of CRISPR-cas loci. Expression of the Cas protein complex and crRNA guide prepares the cell for the cleavage (arrowhead) of incoming viruses.
See this image and copyright information in PMC

Comment on

References

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