Scanning tunneling and transmission electron microscopy on identical areas of biological specimens
- PMID: 2800041
- DOI: 10.1016/0304-3991(89)90056-9
Scanning tunneling and transmission electron microscopy on identical areas of biological specimens
Abstract
A methodology for tip and specimen-support manufacturing is described which allows for scanning tunneling microscopy (STM) and transmission electron microscopy (TEM) on identical areas of biological specimens, at comparable resolution. Topographs and dI/ds-maps were used to investigate tip-specimen interaction on native air-dried phage T4 polyheads where individual capsomeres and structural alterations upon repetitive scans have been observed at a tunnel current of 0.5 pA.
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