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Review
. 2016 Dec 18;9(12):1820-1823.
doi: 10.18240/ijo.2016.12.20. eCollection 2016.

Therapeutic and inducing effect of corneal crosslinking on infectious keratitis

Liang-Zhu Jiang  1 , Shi-Yan Qiu  2 , Zhi-Wei Li  3 , Xiao Zhang  3 , Xiang-Chen Tao  3 , Guo-Ying Mu  3
Affiliations
Review

Therapeutic and inducing effect of corneal crosslinking on infectious keratitis

Liang-Zhu Jiang et al. Int J Ophthalmol. .

Abstract

The corneal crosslinking (CXL) with riboflavin and ultraviolet-A (UVA) is a new therapy method to successfully treat infectious keratitis in clinical practice. However, there are rare reports on the complications of CXL such as the secondary keratitis. The diverse clinical outcomes on keratitis have highlighted the necessity to further evaluate the efficacy and complications of CXL. We reviewed the positive and negative reports on UVA/riboflavin related with keratitis and provided our opinion on the therapeutic and side effect of UVA/riboflavin crosslinking on keratitis.

Keywords: corneal crosslinking; keratitis; theraputic and inducing effect.

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References

    1. Wollensak G, Spörl E, Seiler T. Treatment of keratoconus by collagen cross linking. Ophthalmologe. 2003;100(1):44–49. - PubMed
    1. Hafezi F, Kanellopoulos J, Wiltfang R, Seiler T. Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis. J Cataract Refract Surg. 2007;33(12):2035–2040. - PubMed
    1. Vazirani J, Vaddavalli PK. Cross-linking for microbial keratitis. Indian J Ophthalmol. 2013;61(8):441–444. - PMC - PubMed
    1. Martins SA, Combs JC, Noguera G, Camacho W, Wittmann P, Walther R, Cano M, Dick J, Behrens A. Antimicrobial efficacy of riboflavin/UVA combination (365 nm) in vitro for bacterial and fungal isolates: a potential new treatment for infectious keratitis. Invest Ophthalmol Vis Sci. 2008;49(8):3402–3408. - PubMed
    1. Schrier A, Greebel G, Attia H, Trokel S, Smith EF. In vitro antimicrobial efficacy of riboflavin and ultraviolet light on Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and Pseudomonas aeruginosa. J Refract Surg. 2009;25(9):S799–S802. - PubMed

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