Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2018 Mar;57(2):679-688.
doi: 10.1007/s00394-016-1355-1. Epub 2016 Dec 21.

Dietary intake and major food sources of polyphenols in people with type 2 diabetes: The TOSCA.IT Study

M Vitale  1 , M Masulli  1 , A A Rivellese  1 , E Bonora  2 , F Cappellini  3 , A Nicolucci  4 , S Squatrito  5 , D Antenucci  6 , A Barrea  7 , C Bianchi  8 , F Bianchini  9 , L Fontana  10 , P Fornengo  11 , F Giorgino  12 , A Gnasso  13 , E Mannucci  14 , A Mazzotti  15 , R Nappo  1 , A P Palena  16 , P Pata  17 , G Perriello  18 , S Potenziani  19 , R Radin  20 , L Ricci  21 , F Romeo  22 , C Santini  23 , M Scarponi  24 , R Serra  25 , A Timi  18 , A A Turco  1 , M Vedovato  26 , D Zavaroni  27 , S Grioni  28 , G Riccardi  1 , O Vaccaro  29 ; TOSCA.IT Study Group
Collaborators, Affiliations
Observational Study

Dietary intake and major food sources of polyphenols in people with type 2 diabetes: The TOSCA.IT Study

M Vitale et al. Eur J Nutr. 2018 Mar.

Abstract

Purpose: Proper evaluation of polyphenols intake at the population level is a necessary step in order to establish possible associations with health outcomes. Available data are limited, and so far no study has been performed in people with diabetes. The aim of this work was to document the intake of polyphenols and their major food sources in a cohort of people with type 2 diabetes and in socio-demographic subgroups.

Methods: We studied 2573 men and women aged 50-75 years. Among others, anthropometry was measured by standard protocol and dietary habits were investigated by food frequency questionnaire (EPIC). The intake of polyphenols was evaluated using US Department of Agriculture and Phenol-Explorer databases.

Results: The mean total polyphenol intake was 683.3 ± 5.8 mg/day. Non-alcoholic beverages represented the main food source of dietary polyphenols and provided 35.5% of total polyphenol intake, followed by fruits (23.0%), alcoholic beverages (14.0%), vegetables (12.4%), cereal products and tubers (4.6%), legumes (3.7%) and oils (2.1%); chocolate, cakes and nuts are negligible sources of polyphenols in this cohort. The two most important polyphenol classes contributing to the total intake were flavonoids (47.5%) and phenolic acids (47.4%). Polyphenol intake increased with age and education level and decreased with BMI; furthermore, in the northern regions of Italy, the polyphenol intake was slightly, but significantly higher than in the central or southern regions.

Conclusions: The study documents for the first time the intake of polyphenols and their main food sources in people with diabetes using validated and complete databases of the polyphenol content of food. Compared with published data, collected in people without diabetes, these results suggest a lower intake and a different pattern of intake in people with diabetes.

Keywords: Age; BMI; Diabetes; Diet; Flavonoids; Food groups; Geographical area; Intake; Phenolic acids; Polyphenols; TOSCA.IT study.

PubMed Disclaimer

References

    1. Nutr Metab Cardiovasc Dis. 2014 Jun;24(6):639-47 - PubMed
    1. Database (Oxford). 2010;2010:bap024 - PubMed
    1. Eur J Nutr. 2016 Jun;55(4):1359-75 - PubMed
    1. Am J Clin Nutr. 2005 Jan;81(1 Suppl):230S-242S - PubMed
    1. Crit Rev Food Sci Nutr. 2017 Mar 24;57(5):975-986 - PubMed

Publication types

MeSH terms

LinkOut - more resources