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. 2017 Apr;27(2):113-116.
doi: 10.1007/s10286-016-0392-4. Epub 2016 Dec 22.

Cardiovascular profile in postural orthostatic tachycardia syndrome and Ehlers-Danlos syndrome type III

Jem L Cheng  1 , Jason S Au  1 , Juan C Guzman  2 , Carlos A Morillo  2 , Maureen J MacDonald  3
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Cardiovascular profile in postural orthostatic tachycardia syndrome and Ehlers-Danlos syndrome type III

Jem L Cheng et al. Clin Auton Res. 2017 Apr.

Abstract

The cardiovascular profile of postural orthostatic tachycardia syndrome + Ehlers-Danlos syndrome hypermobility type (POTS + EDSIII) has not been described, despite suggestions that it plays a role in orthostatic intolerance. We studied nine individuals diagnosed with POTS + EDSIII and found that the arterial stiffness and cardiac profiles of patients with POTS + EDSIII were comparable to those of age- and sex-matched controls, suggesting an alternate explanation for orthostatic intolerance.

Keywords: Cardiovascular physiology; Echocardiography; Ehlers–Danlos syndrome type III; Postural orthostatic tachycardia syndrome; Vascular stiffness.

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