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Case Reports
. 2016 Dec;42(12):1836-1837.
doi: 10.1016/j.jcrs.2016.11.004.

Anaphylactic reaction secondary to topical preoperative moxifloxacin

Michael A Ullman  1 , Kirsten J Midgley  2 , Jocelyn Kim  2 , Saul Ullman  2
Affiliations
Case Reports

Anaphylactic reaction secondary to topical preoperative moxifloxacin

Michael A Ullman et al. J Cataract Refract Surg. 2016 Dec.

Abstract

We report a case of anaphylactic shock following topical administration of moxifloxacin for endophthalmitis prophylaxis prior to cataract surgery. Immunoglobulin E (IgE) serology and IgE skin testing confirmed the anaphylactic etiology. Phacoemulsification with posterior chamber intraocular lens implantation was later performed with identical preoperative preparation except for the exclusion of moxifloxacin; no anaphylactic response occurred. To our knowledge, this is the first report of an anaphylactic response to topical moxifloxacin.

Financial disclosure: None of the authors has a financial or proprietary interest in any material or method mentioned.

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