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Review
. 2016 Dec 21;21(12):1759.
doi: 10.3390/molecules21121759.

Preventive Effects of Catechins on Cardiovascular Disease

Xiao-Qiang Chen  1 , Ting Hu  2 , Yu Han  3 , Wei Huang  4 , Hai-Bo Yuan  5 , Yun-Tian Zhang  6 , Yu Du  7 , Yong-Wen Jiang  8
Affiliations
Review

Preventive Effects of Catechins on Cardiovascular Disease

Xiao-Qiang Chen et al. Molecules. .

Abstract

Catechins are polyphenolic phytochemicals with many important physiological activities that play a multifaceted health care function in the human body, especially in the prevention of cardiovascular disease. In this paper, various experimental and clinical studies have revealed the role of catechins in the prevention and treatment of cardiovascular disorders, and we review the preventive effects of catechins on cardiovascular disease from the following aspects: Regulating lipid metabolism, regulating blood lipid metabolism, vascular endothelial protection, and reducing blood pressure.

Keywords: cardiovascular disease; catechins; health care.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The structures of four kinds of catechins: epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG), and epigallocatechin gallate (EGCG) [25].
Figure 2
Figure 2
Mechanism of EGCG auto-oxidation and dimerization.
See this image and copyright information in PMC

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References

    1. Xiang L.P., Wang A., Ye J.H., Zheng X.Q., Polito C.A., Lu J.L., Li Q.S., Liang Y.R. Suppressive effects of tea catechins on breast cancer. Nutrients. 2016;8:458. doi: 10.3390/nu8080458. - DOI - PMC - PubMed
    1. Matsui T. Condensed catechins and their potential health-benefits. Eur. J. Pharmacol. 2015;765:495–502. doi: 10.1016/j.ejphar.2015.09.017. - DOI - PubMed
    1. Assuncao M., Andrade J.P. Protective action of green tea catechins in neuronal mitochondria during aging. Front. Biosci. Landmark Ed. 2015;20:247–262. - PubMed
    1. Pasrija D., Anandharamakrishnan C. Techniques for extraction of green tea polyphenols: A review. Food Bioprocess Technol. 2015;8:935–950. doi: 10.1007/s11947-015-1479-y. - DOI
    1. Berry J.D., Dyer A., Cai X., Garside D.B., Ning H.Y., Thomas A., Greenland P., van Horn L., Tracy R.P., Lloyd-Jones D.M. Lifetime Risks of Cardiovascular Disease. N. Engl. J. Med. 2012;366:321–329. doi: 10.1056/NEJMoa1012848. - DOI - PMC - PubMed

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