A little CFTR can change a lot: slowing cystic fibrosis progression

Steven M Rowe¹

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Affiliation

¹ Departments of Medicine, Pediatrics, Cell Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA. Electronic address: smrowe@uab.edu.

PMID: 28011036
DOI: 10.1016/S2213-2600(16)30465-9

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A little CFTR can change a lot: slowing cystic fibrosis progression

Steven M Rowe. Lancet Respir Med. 2017 Feb.

. 2017 Feb;5(2):86-87.

doi: 10.1016/S2213-2600(16)30465-9. Epub 2016 Dec 21.

Author

Steven M Rowe¹

Affiliation

¹ Departments of Medicine, Pediatrics, Cell Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA. Electronic address: smrowe@uab.edu.

PMID: 28011036
DOI: 10.1016/S2213-2600(16)30465-9

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Assessment of safety and efficacy of long-term treatment with combination lumacaftor and ivacaftor therapy in patients with cystic fibrosis homozygous for the F508del-CFTR mutation (PROGRESS): a phase 3, extension study.
Konstan MW, McKone EF, Moss RB, Marigowda G, Tian S, Waltz D, Huang X, Lubarsky B, Rubin J, Millar SJ, Pasta DJ, Mayer-Hamblett N, Goss CH, Morgan W, Sawicki GS. Konstan MW, et al. Lancet Respir Med. 2017 Feb;5(2):107-118. doi: 10.1016/S2213-2600(16)30427-1. Epub 2016 Dec 21. Lancet Respir Med. 2017. PMID: 28011037 Clinical Trial.

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P30 DK072482/DK/NIDDK NIH HHS/United States

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A little CFTR can change a lot: slowing cystic fibrosis progression

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A little CFTR can change a lot: slowing cystic fibrosis progression

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Grants and funding

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Medical