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Review
. 2017 Mar;47(2):435-450.
doi: 10.1016/j.cvsm.2016.10.018. Epub 2016 Dec 21.

Lipid Therapy for Intoxications

Affiliations
Review

Lipid Therapy for Intoxications

Joris Henricus Robben et al. Vet Clin North Am Small Anim Pract. 2017 Mar.

Abstract

This review discusses the use of intravenous lipid emulsion (ILE) in the treatment of intoxications with lipophilic agents in veterinary medicine. Despite growing scientific evidence that ILE has merit in the treatment of certain poisonings, there is still uncertainty on the optimal composition of the lipid emulsion, the dosing, the mechanism of action, and the efficacy. Therefore, a critical view of the clinician on the applicability of this modality in intoxications is still warranted. The use of ILE therapy is advocated as an antidote in cases of intoxications with some lipophilic substances.

Keywords: Emulsion; Fat; ILE; Intralipid; Lipid; Lipid resuscitation therapy; Poisoning; Toxin.

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