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Case Reports
. 2017 Mar-Apr:16:49-51.
doi: 10.1016/j.tmaid.2016.12.005. Epub 2016 Dec 22.

Surviving Naegleria fowleri infections: A successful case report and novel therapeutic approach

Travis W Heggie  1 , Thomas Küpper  2
Affiliations
Case Reports

Surviving Naegleria fowleri infections: A successful case report and novel therapeutic approach

Travis W Heggie et al. Travel Med Infect Dis. 2017 Mar-Apr.

Abstract

Naegleria fowleri is a deadly human pathogen recognized as the causative agent of Primary Amoebic Meningitis (PAM). N. fowleri is commonly found in warm freshwater environments such as natural or man-made lakes, hot springs, and resort spas frequented by tourists. PAM infections have a mortality rate between 95 and 99% with minimal progress being made toward a successful treatment therapy. We report the case of a 12-year old American female who survived a PAM infection and propose a new drug therapy which includes the antimicrobial drug Miltefosine.

Keywords: Miltefosine; Naegleria fowleri; Primary Amoebic Meningitis.

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Comment in

  • Naegleria fowleri infections.
    Linam WM, Cope JR. Linam WM, et al. Travel Med Infect Dis. 2017 Nov-Dec;20:65. doi: 10.1016/j.tmaid.2017.05.007. Epub 2017 May 10. Travel Med Infect Dis. 2017. PMID: 28501613 Free PMC article. No abstract available.
  • Surviving Naegleria fowleri infections: Response.
    Heggie TW. Heggie TW. Travel Med Infect Dis. 2017 Nov-Dec;20:66. doi: 10.1016/j.tmaid.2017.11.010. Travel Med Infect Dis. 2017. PMID: 29241583 No abstract available.

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