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. 1977 Mar 4:284:697-702.
doi: 10.1111/j.1749-6632.1977.tb22005.x.

De novo cell-free synthesis of human interferon

S Pestka, J McInnes, D Weiss, E A Havell, J Vilcek

De novo cell-free synthesis of human interferon

S Pestka et al. Ann N Y Acad Sci. .

Abstract

Biologically active human interferon was synthesized de novo in a cell-free mouse extract stimulated with messenger RNA from induced human fibroblasts. The identity of the antiviral activity as human interferon was demonstrated by its antigenic and species specificity. Some characteristics of the cell-free synthesis were described.

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