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Case Reports
. 2016 Nov 9:13:20-23.
doi: 10.1016/j.amsu.2016.11.001. eCollection 2017 Jan.

A case report of small bowel perforation secondary to cytomegalovirus related immune reconstitution inflammatory syndrome in an AIDS patient

Eva María Gutiérrez-Delgado  1 , Hiram Villanueva-Lozano  1 , Miguel J García Rojas-Acosta  2 , Ivett C Miranda-Maldonado  3 , Javier Ramos-Jiménez  1
Affiliations
Case Reports

A case report of small bowel perforation secondary to cytomegalovirus related immune reconstitution inflammatory syndrome in an AIDS patient

Eva María Gutiérrez-Delgado et al. Ann Med Surg (Lond). .

Abstract

Non-traumatic small bowel perforation is rare in adults but carries a high morbidity and mortality. The diagnosis is made on clinical suspicion, and the most common causes in developing countries are infectious diseases, being cytomegalovirus infection in immunocompromised patients the main etiology. We describe a patient with a recently diagnosed advanced stage HIV infection and an intestinal perforation associated with cytomegalovirus immune reconstitution inflammatory syndrome after highly active antiretroviral therapy initiation.

Keywords: Cytomegalovirus; IRIS; Intestinal perforation; Non-traumatic perforation; Small bowel.

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Figures

Fig. 1
Fig. 1
Arrow indicates cytoplasmic inclusion in cytomegalovirus-infected cell.
Fig. 2
Fig. 2
Cytomegalovirus infected cells evidenced by immunohistochemistry.
See this image and copyright information in PMC

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