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. 2016 Sep;3(3):277-292.
doi: 10.1007/s40501-016-0088-3. Epub 2016 Jul 2.

Novel Therapeutics for Addiction: Behavioral and Neuroeconomic Approaches

Warren K Bickel  1 , Alexandra M Mellis  1 , Sarah E Snider  1 , Lara Moody  1 , Jeffrey S Stein  1 , Amanda J Quisenberry  1
Affiliations

Novel Therapeutics for Addiction: Behavioral and Neuroeconomic Approaches

Warren K Bickel et al. Curr Treat Options Psychiatry. 2016 Sep.

Abstract

The maturing fields of behavioral- and neuro-economics provides conceptual understanding of the Competing Neurobehavioral Decision Systems theory (CNDS) and reinforcer pathology (i.e. high valuation of and excessive preference for drug reinforcers) allowing us to coherently categorize treatments into a theoretically comprehensive framework of addiction. In this chapter, we identify and clarify how existing and novel interventions can ameliorate reinforcer pathology in light of the CNDS and be leveraged to treat addiction.

Keywords: Addiction; Competing Neurobehavioral Decision Systems theory; behavioral economics; delay discounting; drug demand; impulsivity.

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Figures

Fig. 1
Fig. 1
Behavioral control in the Competing Neurobehavioral Decision Systems theory. Combined strengths of the impulsive and executive systems may fall at any coordinate in this two-dimensional space, with behavior controlled by relative contributions of each system (see color gradient). The diagonal line represents regulatory balance between impulsive and executive systems. In this illustration, interacting system strengths falling at coordinates A and B produce identical levels of impulsive behavior, with both producing more impulsive behavior than those at coordinate C
See this image and copyright information in PMC

References

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