Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016;2(3):10.16966/2380-548X.129.
doi: 10.16966/2380-548X.129. Epub 2016 Jul 11.

Clinical Practice Guideline for Management of Primary Aldosteronism: What is New in the 2016 Update?

Affiliations

Clinical Practice Guideline for Management of Primary Aldosteronism: What is New in the 2016 Update?

Damian G Romero et al. Int J Endocrinol Metab Disord. 2016.

Abstract

Primary Aldosteronism is the single most common cause of secondary hypertension and is associated with increased target organ injury. The Endocrine Society has recently released the updated Clinical Practice Guideline for Primary Aldosteronism entitled "The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline". We review the updated Clinical Practice Guideline, highlighting the new recommendations and the implications that they may have in clinical practice. The recognition by the Endocrine Society's Task Force that Primary Aldosteronism is a public health issue and that the population at risk for screening should be significantly expanded will surely have an impact in the clinical practice which hopefully will translate in better detection, diagnosis and treatment of patients with Primary Aldosteronism.

Keywords: Adrenocorticotrophic hormone; Aldosterone-producing adenoma; Primary Aldosteronism.

PubMed Disclaimer

References

    1. Funder JW, Carey RM, Mantero F, Murad MH, Reincke M, et al. The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016;101:1889–1916. - PubMed
    1. Bollag WB. Regulation of aldosterone synthesis and secretion. Compr Physiol. 2014;4:1017–1055. - PubMed
    1. Connell JM, MacKenzie SM, Freel EM, Fraser R, Davies E. A lifetime of aldosterone excess: long-term consequences of altered regulation of aldosterone production for cardiovascular function. Endocr Rev. 2008;29:133–154. - PubMed
    1. Spat A, Hunyady L. Control of aldosterone secretion: a model for convergence in cellular signaling pathways. Physiol Rev. 2004;84:489–539. - PubMed
    1. Jaisser F, Farman N. Emerging Roles of the Mineralocorticoid Receptor in Pathology: Toward New Paradigms in Clinical Pharmacology. Pharmacol Rev. 2016;68:49–75. - PubMed

LinkOut - more resources