New modified trichothecenes accumulated in solid culture by mutant strains of Fusarium sporotrichioides
- PMID: 2802605
- PMCID: PMC203055
- DOI: 10.1128/aem.55.9.2195-2199.1989
New modified trichothecenes accumulated in solid culture by mutant strains of Fusarium sporotrichioides
Abstract
Mutant strains of Fusarium sporotrichioides NRRL 3299 deficient in the ability to synthesize T-2 toxin were examined on solid rice medium. Five novel alicyclic trichothecenes were isolated: 11 alpha-hydroxytrichodiene; tricho-9-ene-2 alpha,3 alpha,11 alpha-triol; tricho-9-ene-2 alpha,3 alpha,8 alpha,11 alpha-tetraol; tricho-9-ene-2 alpha,3 alpha,8 beta,11 alpha-tetraol; and tricho-9-ene-2 alpha,3 alpha,11 alpha,16-tetraol.
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