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Case Reports
. 1989 Oct;46(10):1104-6.
doi: 10.1001/archneur.1989.00520460090018.

Chronic manganese intoxication

C C Huang  1 , N S Chu, C S Lu, J D Wang, J L Tsai, J L Tzeng, E C Wolters, D B Calne
Affiliations
Case Reports

Chronic manganese intoxication

C C Huang et al. Arch Neurol. 1989 Oct.

Abstract

We report six cases of chronic manganese intoxication in workers at a ferromanganese factory in Taiwan. Diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. In addition, increased manganese levels in the environmental air were established. The patients showed a bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.

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