Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Dec 1;2016(12):omw090.
doi: 10.1093/omcr/omw090. eCollection 2016 Dec.

Endobronchial pleomorphic adenoma

Syed Rizwan Ali  1 , Andrea Valeria Arrossi  2 , Atul C Mehta  3 , Laura Frye  4 , Peter Mazzone  3 , Francisco Almeida  3
Affiliations

Endobronchial pleomorphic adenoma

Syed Rizwan Ali et al. Oxf Med Case Reports. .

Abstract

Pleomorphic adenomas are the most common tumors of the salivary glands. Rarely, they occur as benign lesions in the lungs in both the central airways and the lung parenchyma. Herein, we present a case of a 60-year-old smoker who was incidentally found to have an endobronchial mass while undergoing evaluation for a lung nodule. During bronchoscopy, a smooth globular nodule was identified at the main carina and removed using electrocautery snare. Histopathology examination revealed this to be a pleomorphic adenoma.

Keywords: Bronchoscopy; Pleomorphic adenoma.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
Bronchoscopic view of the smooth mass at the carina (A) that was removed using electrocautery (B). Gross specimen after removal showing a smooth polypoid tumor with tan and white lobulated cut surface (C). Photomicrograph showing lobules of chondromyxoid tissue (*) and cellular areas (#) microscopically (D, E). The lesion contains tubules lined by inner ductal cells (thick arrow) and outer myoepithelial cells (thin arrow) (1C gross picture; 1D hematoxylin and eosin 0.7×; 1E hematoxylin and eosin 12.4×).
See this image and copyright information in PMC

References

    1. Guzzo M, Locati LD, Prott FJ, Gatta G, McGurk M, Licitra L. Major and minor salivary gland tumors. Crit Rev Oncol Hematol 2010;74:134–48. http://dx.doi.org/10.1016/j.critrevonc.2009.10.004. - PubMed
    1. Baghai-Wadji M, Sianati M, Nikpour H, Koochekpour S. Pleomorphic adenoma of the trachea in an 8-year-old boy: a case report. J Pediatr Surg 2006;41:e23–6. http://dx.doi.org/10.1016/j.jpedsurg.2006.04.008. - PubMed
    1. Moran CA, Suster S, Askin FB, Koss MN. Benign and malignant salivary gland-type mixed tumors of the lung. Clinicopathologic and immunohistochemical study of eight cases. Cancer 1994;73:2481–90. http://dx.doi.org/10.1002/1097-0142(19940515)73:10<2481::AID-CNCR2820731.... - PubMed
    1. Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG. WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart, 4th edn Lyon: International Agency for Research on Cancer, 2015. - PubMed
    1. Weissferdt A, Moran CA. Pulmonary salivary gland-type tumors with features of malignant mixed tumor (carcinoma ex pleomorphic adenoma): a clinicopathologic study of five cases. Am J Clin Pathol 2011;136:793–8. http://dx.doi.org/10.1309/AJCP50FBZWSACKIP. - PubMed

LinkOut - more resources