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Review
. 2016;10(4):163-169.
doi: 10.1007/s12281-016-0268-z. Epub 2016 Dec 7.

Pathogenesis of Fungal Infections in Cystic Fibrosis

Craig Williams  1 , Ranjith Ranjendran  2 , Gordon Ramage  2
Affiliations
Review

Pathogenesis of Fungal Infections in Cystic Fibrosis

Craig Williams et al. Curr Fungal Infect Rep. 2016.

Abstract

For a long time, the microbiology of cystic fibrosis has been focussed on Pseudomonas aeruginosa and associated Gram-negative pathogens. An increasing body of evidence has been compiled demonstrating an important role for moulds and yeasts within this complex patient group. Whether or not fungi are active participants, spectators or transient passersby remain to be elucidated. However, functionally, they do appear to play a contributory role in pathogenesis, albeit we do not know if this is a direct or indirect effect. The following review examines some of the key evidence for the role of fungi in CF pathogenesis.

Keywords: Cystic fibrosis; Fungal infections; Pathogenesis; Pseudomonas aeruginosa; Review.

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Conflict of interest statement

Craig Williams, Ranjith Ranjendran and Gordon Ramage declare that they have no conflict of interest. Human and Animal Rights and Informed Consent This article does not contain any studies with human or animal subjects performed by any of the authors.

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