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. 2018 Feb;38(1):11-18.
doi: 10.1007/s10792-016-0401-6. Epub 2016 Dec 29.

Treatment outcome in patients with presumed tubercular uveitis at a tertiary referral eye care centre in Singapore

Leslie Ang  1 , Aera Kee  2 , Tun Hang Yeo  1 , V G Dinesh  3 , Su Ling Ho  1 , Stephen C Teoh  1   4 , Rupesh Agrawal  5
Affiliations

Treatment outcome in patients with presumed tubercular uveitis at a tertiary referral eye care centre in Singapore

Leslie Ang et al. Int Ophthalmol. 2018 Feb.

Abstract

Aim: To report the clinical features and outcome of patients with presumed tubercular uveitis (TBU).

Methods: Retrospective analysis of patients with presumed TBU at a tertiary referral eye care centre in Singapore between 2007 and 2012 was done. Main outcome measures were failure of complete resolution of uveitis or recurrence of inflammation.

Results: Fifty three patients with mean age of 44.18 ± 15.26 years with 54.72% being males were included. 19 (35.85%) had bilateral involvement, with panuveitis and anterior uveitis being the most common presentations. 36 (67.92%) patients received antitubercular therapy (ATT), and 28 received concurrent systemic steroids. 15 (28.30%) eyes of 11 (30.55%) patients in the ATT group and 4 (21.05%) eyes of 3 (17.64%) patients in the non-ATT group had treatment failure (p value = 0.51).

Conclusion: The use of ATT, with or without concurrent corticosteroid, may not have a statistically significant impact in improving treatment success in patients with presumed TBU.

Keywords: Antitubercular therapy; Panuveitis; Steroids; Tubercular uveitis; Tuberculosis.

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