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. 2017 May/Jun;34(3):196-202.
doi: 10.1177/1043454216680596. Epub 2016 Dec 30.

Risk for Health Care-Associated Bloodstream Infections in Pediatric Oncology Patients With Various Malignancies

Cara B Thurman  1 , Maura Abbott  1 , Jinfang Liu  1 , Elaine Larson  1
Affiliations

Risk for Health Care-Associated Bloodstream Infections in Pediatric Oncology Patients With Various Malignancies

Cara B Thurman et al. J Pediatr Oncol Nurs. 2017 May/Jun.

Abstract

This was a retrospective cohort study to identify the rates, predictors, and outcomes of health care-associated bloodstream infections (HA-BSI) among children with solid tumors, lymphoma, lymphoid leukemia, and myeloid leukemia. The study population included 4500 children ≤18 years old at a pediatric hospital in New York City from 2006 to 2014. A total of 147 HA-BSI cases were identified; using multivariable logistic regression modeling, children with a hematologic diagnosis (lymphoma, lymphoid leukemia, myeloid leukemia) were at greater risk for HA-BSI than those with a solid tumor diagnosis (all P values <.0001). The odds of mortality for patients with HA-BSI were 6.98 (95% confidence interval 3.02-16.10) times that of those without HA-BSI. Although malignancy type was identified as risk factor for HA-BSI, there was no significant difference in overall mortality from HA-BSI by tumor type ( P = .51).

Keywords: epidemiology; health care–associated infections; hematology; oncology.

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Conflict of interest statement

Declaration of Conflicting Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Algorithm to identify health care–associated bloodstream infection.
See this image and copyright information in PMC

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