The incredible complexity of RNA splicing
- PMID: 28038679
- PMCID: PMC5203710
- DOI: 10.1186/s13059-016-1121-y
The incredible complexity of RNA splicing
Abstract
Alternative splice isoforms are common and important and have been shown to impact many human diseases. A new study by Nellore et al. offers a comprehensive study of splice junctions in humans by re-analyzing over 21,500 public human RNA sequencing datasets.
Comment on
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Human splicing diversity and the extent of unannotated splice junctions across human RNA-seq samples on the Sequence Read Archive.Genome Biol. 2016 Dec 30;17(1):266. doi: 10.1186/s13059-016-1118-6. Genome Biol. 2016. PMID: 28038678 Free PMC article.
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- BB/J004243/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom
- BBS/E/D/20211551/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom
- BBS/E/D/20211552/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom
- BB/J004235/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom
- BBS/E/D/20310000/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom
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