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Review
. 2016 Dec;17(4):322-326.

The process of mineralisation in the development of human tooth

Affiliations
  • PMID: 28045323
Review

The process of mineralisation in the development of human tooth

S Caruso et al. Eur J Paediatr Dent. 2016 Dec.

Abstract

Tooth development and mineralisation are processes that derive from different tissues interactions, in particular ectodermal and mesenchymal layers. These interactions are responsible for the formation of unique structures with a particular chemical composition. Despite differences, mineralised tissues are similar and they derive by highly concerted extracellular processes that involve matrix proteins, proteases, and mineral ion fluxes that collectively regulate the nucleation, growth and organisation of forming mineral crystals. This review aims at explaining mineralisation, its stages and when damage occurs and alters the hard tissues structure.

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