The Clinical High-Risk State for Psychosis (CHR-P), Version II

doi:10.1093/schbul/sbw158

. 2017 Jan;43(1):44-47.

doi: 10.1093/schbul/sbw158.

The Clinical High-Risk State for Psychosis (CHR-P), Version II

Paolo Fusar-Poli^{1

2}

Affiliations

¹ Department of Psychosis Studies, Institute of Psychiatry , Psychology and Neuroscience, King's College London, London, UK; paolo.fusar-poli@kcl.ac.uk.
² OASIS Service, South London and the Maudsley NHS Foundation Trust, London, UK.

PMID: 28053129
PMCID: PMC5216870
DOI: 10.1093/schbul/sbw158

The Clinical High-Risk State for Psychosis (CHR-P), Version II

Paolo Fusar-Poli. Schizophr Bull. 2017 Jan.

. 2017 Jan;43(1):44-47.

doi: 10.1093/schbul/sbw158.

Author

Paolo Fusar-Poli^{1

2}

Affiliations

¹ Department of Psychosis Studies, Institute of Psychiatry , Psychology and Neuroscience, King's College London, London, UK; paolo.fusar-poli@kcl.ac.uk.
² OASIS Service, South London and the Maudsley NHS Foundation Trust, London, UK.

PMID: 28053129
PMCID: PMC5216870
DOI: 10.1093/schbul/sbw158

Abstract

The Clinical High-Risk state for psychosis (CHR-P) paradigm was introduced about 2 decades ago. Over this period of time accumulating knowledge has been gained. Conceptual advancements involve new knowledge into risk enrichment and the impact of recruitment strategies, specificity for prediction of psychotic and nonpsychotic mental disorders and heterogeneity of psychosis risk among the different CHR-P subgroups. The current special issue advances current knowledge on deconstructing the CHR-P paradigm across its 3 subgroups: genetic risk, attenuated psychotic symptoms, and short-lived and remitting psychotic episodes. A conceptual revision of the paradigm (Version II) is suggested and supported by 3 original studies published in this special issue.

Keywords: ARMS; SIPS; UHR; psychosis; risk; schizophrenia.

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Fusar-Poli P, De Micheli A, Patel R, Signorini L, Miah S, Spencer T, McGuire P. Fusar-Poli P, et al. Schizophr Bull. 2020 Sep 21;46(5):1114-1125. doi: 10.1093/schbul/sbaa040. Schizophr Bull. 2020. PMID: 32303767 Free PMC article.
Lack of Diagnostic Pluripotentiality in Patients at Clinical High Risk for Psychosis: Specificity of Comorbidity Persistence and Search for Pluripotential Subgroups.
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References

1. Yung AR, McGorry PD, McFarlane CA, Jackson HJ, Patton GC, Rakkar A. Monitoring and care of young people at incipient risk of psychosis. Schizophr Bull. 1996;22:283–303. - PubMed
1. Yung A, Yuen H, McGorry P, et al. Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental States. ANZJP. 2005;39:964–971. - PubMed
1. NICE. Psychosis and schizophrenia in children and young people: recognition and management. 2013. https://www.nice.org.uk/guidance/cg155 . - PubMed
1. NHS England. Achieving better access to mental health services by 2020. 2014. https://www.gov.uk/government/publications/mental-health-services-achiev....
1. Fusar-Poli P, Cappucciati M, Rutigliano G, et al. At risk or not at risk? A meta-analysis of the prognostic accuracy of psychometric interviews for psychosis prediction. World Psychiatry. 2015;14:322–332. - PMC - PubMed

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[1] Yung AR, McGorry PD, McFarlane CA, Jackson HJ, Patton GC, Rakkar A. Monitoring and care of young people at incipient risk of psychosis. Schizophr Bull. 1996;22:283–303. - PubMed

[2] Yung AR, McGorry PD, McFarlane CA, Jackson HJ, Patton GC, Rakkar A. Monitoring and care of young people at incipient risk of psychosis. Schizophr Bull. 1996;22:283–303. - PubMed

[3] Yung A, Yuen H, McGorry P, et al. Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental States. ANZJP. 2005;39:964–971. - PubMed

[4] Yung A, Yuen H, McGorry P, et al. Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental States. ANZJP. 2005;39:964–971. - PubMed

[5] NICE. Psychosis and schizophrenia in children and young people: recognition and management. 2013. https://www.nice.org.uk/guidance/cg155 . - PubMed

[6] NICE. Psychosis and schizophrenia in children and young people: recognition and management. 2013. https://www.nice.org.uk/guidance/cg155 . - PubMed

[7] NHS England. Achieving better access to mental health services by 2020. 2014. https://www.gov.uk/government/publications/mental-health-services-achiev....

[8] NHS England. Achieving better access to mental health services by 2020. 2014. https://www.gov.uk/government/publications/mental-health-services-achiev....

[9] Fusar-Poli P, Cappucciati M, Rutigliano G, et al. At risk or not at risk? A meta-analysis of the prognostic accuracy of psychometric interviews for psychosis prediction. World Psychiatry. 2015;14:322–332. - PMC - PubMed

[10] Fusar-Poli P, Cappucciati M, Rutigliano G, et al. At risk or not at risk? A meta-analysis of the prognostic accuracy of psychometric interviews for psychosis prediction. World Psychiatry. 2015;14:322–332. - PMC - PubMed

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The Clinical High-Risk State for Psychosis (CHR-P), Version II

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The Clinical High-Risk State for Psychosis (CHR-P), Version II

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