Spontaneously developed paraplegia in a patient with Factor V Leiden mutation
- PMID: 28053741
- PMCID: PMC5129424
- DOI: 10.1038/scsandc.2015.39
Spontaneously developed paraplegia in a patient with Factor V Leiden mutation
Erratum in
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Erratum for Spinal Cord Series and Cases content published prior to July 2016.Spinal Cord Ser Cases. 2016 Jul 21;2:16019. doi: 10.1038/scsandc.2016.19. eCollection 2016. Spinal Cord Ser Cases. 2016. PMID: 31265710 Free PMC article.
Abstract
Factor V Leiden (FVL) mutation is the one-point mutation in G1691A in the tenth exon of the gene for Factor V, caused by the substitution of glutamine for arginine at codon 506. We present here a patient with a mutation of the Factor V gene and taking anticoagulant therapy, who became paraplegic following surgery for dural hematoma and spontaneous spinal intramedullary hematoma. His physical examination revealed T5 ASIA A, complete paraplegia. Our case is important in the literature, as being the first case with spinal intramedullary hematoma that developed due to anticoagulant use.
Keywords: Outcomes research; Spinal cord diseases.
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