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Case Reports
. 2016 Sep 15:7:10-12.
doi: 10.1016/j.ebcr.2016.09.003. eCollection 2017.

Dyke-Davidoff-Masson syndrome in a Nigerian

Philip B Adebayo  1 , Amnat Bakare  2 , Modupe M Bello  2 , Opeyemi D Olaewe  2 , Kolawole W Wahab  3
Affiliations
Case Reports

Dyke-Davidoff-Masson syndrome in a Nigerian

Philip B Adebayo et al. Epilepsy Behav Case Rep. .

Abstract

Dyke-Davidoff-Masson syndrome (DDMS) is a rare, but important cause of drug-resistant seizures. Dyke-Davidoff-Masson syndrome is a constellation of clinical features that consists of hemiparesis, seizure, facial asymmetry, and intellectual disability with distinct neuroimaging features. A 27-year-old lady presented to us with drug-resistant epilepsy, hemiparesis, and intellectual disability that necessitated her withdrawal from school. Her brain magnetic resonance imaging (MRI) showed cerebral hemiatrophy, calvarial thickening, and hyperpneumatization of the frontal sinuses consistent with DDMS. We discuss the diagnostic and therapeutic implications of DDMS and advocate early referral and evaluation of people with epilepsy in sub-Saharan African settings.

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Figures

Fig. 1
Figure
Axial sequences of brain MRI in DDMS of the patient. A. Axial T1-weighted MRI showing right cerebral hemiatrophy with prominent sulci and encephalomalacia. B. Axial T1-weighted MRI showing thickened calvarium on the right. C. Axial T2-weighted MRI showing right frontal sinus enlargement and hyperpneumatization. D. Axial T2 FLAIR showing abnormal signal intensity consistent with gliosis.
See this image and copyright information in PMC

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