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Review
. 2017 Jan 4;9(1):18.
doi: 10.3390/toxins9010018.

Forthcoming Challenges in Mycotoxins Toxicology Research for Safer Food-A Need for Multi-Omics Approach

Affiliations
Review

Forthcoming Challenges in Mycotoxins Toxicology Research for Safer Food-A Need for Multi-Omics Approach

Luca Dellafiora et al. Toxins (Basel). .

Abstract

The presence of mycotoxins in food represents a severe threat for public health and welfare, and poses relevant research challenges in the food toxicology field. Nowadays, food toxicologists have to provide answers to food-related toxicological issues, but at the same time they should provide the appropriate knowledge in background to effectively support the evidence-based decision-making in food safety. Therefore, keeping in mind that regulatory actions should be based on sound scientific findings, the present opinion addresses the main challenges in providing reliable data for supporting the risk assessment of foodborne mycotoxins.

Keywords: food toxicology; foodborne diseases; mechanisms of action; multi-omic approach; mycotoxins; regulations; risk assessment.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Example of the multilevel activity of deoxynivalenol.
Figure 2
Figure 2
Understanding of the mechanisms of action of mycotoxins from molecular perspective.

References

    1. Kotsonis F.N., Burdock G.A. Food Toxicology. In: Klaassen C.D., editor. Casarett & Doull’s Toxicology: The Basic Science of Poisons. 8th ed. McGraw-Hill Education; New York, NY, USA: 2013.
    1. Shaw I.C. Chemical residues, food additives and natural toxicants in food—The cocktail effect. Int. J. Food Sci. Tech. 2014;49:2149–2157. doi: 10.1111/ijfs.12606. - DOI
    1. Wu F., Groopman J.D., Pestka J.J. Public health impacts of foodborne mycotoxins. Annu. Rev. Food Sci. Technol. 2014;5:351–372. doi: 10.1146/annurev-food-030713-092431. - DOI - PubMed
    1. Vaghini S., Cilla A., Garcia-Llatas G., Lagarda M.J. Bioaccessibility study of plant sterol-enriched fermented milks. Food Funct. 2016;7:110–117. doi: 10.1039/C5FO00458F. - DOI - PubMed
    1. Schecter A., Papke O., Dellarco M. Dioxin, dibenzofuran, and PCB congeners in cooked and uncooked food. Organohalogen Comp. 1997;33:462–466.

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