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Review
. 2016 Nov:103 Suppl 1:S160-S163.
doi: 10.1016/S0007-4551(16)30374-5.

Utilisation des inhibiteurs de PD-1 dans les hémopathies lymphoïdes

[Article in French]
Laura Bounaix  1 , Mohammed Bendouda  1 , Jacques-Olivier Bay  1 , Richard Lemal  2
Affiliations
Review

Utilisation des inhibiteurs de PD-1 dans les hémopathies lymphoïdes

[Article in French]
Laura Bounaix et al. Bull Cancer. 2016 Nov.

Abstract

ANTI-PD-1 ANTIBODIES THERAPEUTIC USE IN LYMPHOID NEOPLASMS: Immune checkpoints blockade is under investigation in oncology, and has demonstrated its clinical efficacy. In hematology, immune checkpoints blockade is in earlier stages of development, but there are strong evidences of PD-1 blockade anti-tumor efficacy in some lymphoid malignancies. In this review, we will discuss the main clinical results of PD-1 inhibitors in lymphoid neoplasms and the main perspectives of development.

Keywords: Lymphoma; Lymphome; Nivolumab; PD-1.

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