Utilisation des inhibiteurs de PD-1 dans les hémopathies lymphoïdes
- PMID: 28057180
- DOI: 10.1016/S0007-4551(16)30374-5
Utilisation des inhibiteurs de PD-1 dans les hémopathies lymphoïdes
Abstract
ANTI-PD-1 ANTIBODIES THERAPEUTIC USE IN LYMPHOID NEOPLASMS: Immune checkpoints blockade is under investigation in oncology, and has demonstrated its clinical efficacy. In hematology, immune checkpoints blockade is in earlier stages of development, but there are strong evidences of PD-1 blockade anti-tumor efficacy in some lymphoid malignancies. In this review, we will discuss the main clinical results of PD-1 inhibitors in lymphoid neoplasms and the main perspectives of development.
Keywords: Lymphoma; Lymphome; Nivolumab; PD-1.
© 2016 Société Française du Cancer. Publié par Elsevier Masson SAS. Tous droits réservés.
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